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KMID : 1103720100630020107
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Journal of the Korean Society of Radiology
2010 Volume.63 No. 2 p.107 ~ p.113
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Endobronchial Occlusion Stent: A Preliminary Experimental Study
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Choi Yo-Won
Jeong Woo-Kyoung
Lee Seung-Hun
Heo Jeong-Nam
Jeon Seok-Chol
Ko Gi-Young
Song Ho-Young
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Abstract
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Purpose: To evaluate the safety and the technical feasibility of the use of an endobronchial occlusion stent and to get preliminary data for the development of the optimal material required for endobronchial occlusions.
Materials and Methods: A commercialized, self-expandable tracheobronchial stent was modified; one half had a polyurethane cover with an occluded end and the other half was uncovered with a flaring configuration. The occluded end was placed such that it would face the distal lung. Under fluoroscopic guidance, seven stents were placed at the lower lobar bronchus in 6 mini-pigs. The bronchial obstruction was examined immediately after stent placement. Chest radiographs were taken at days 1, 7, 14, and 28 after stent placement and the removed airways from two, two, one, and one mini-pigs sacrificed on corresponding days were examined for the maintenance of bronchial obstruction.
Results: Stents were successfully placed and induced the immediate bronchial obstruction in all mini-pigs. Five of seven airways with occlusion stents maintained an obstruction until the mini-pigs were sacrificed. Proximal stent migration occurred in two mini-pigs (29%), and pulmonary consolidations were observed distal to four of the stents (57%).
Conclusion: The placement of an endobronchial occlusion stent and the obstruction of targeted bronchi seem to be feasible, but an add-on check valve should be considered to prevent stent migration and obstructive pneumonia.
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KEYWORD
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Bronchial Fistula, Stents, Respiratory Tract Fistula
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